models (simplified and simulink) Search Results


stateflow discrete time models  (MathWorks Inc)
96
MathWorks Inc stateflow discrete time models
Stateflow Discrete Time Models, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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simscape electrical blockset library  (MathWorks Inc)
94
MathWorks Inc simscape electrical blockset library
Simscape Electrical Blockset Library, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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simulink model  (MathWorks Inc)
96
MathWorks Inc simulink model
Simulink Model, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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guidance control schemes  (MathWorks Inc)
96
MathWorks Inc guidance control schemes
Guidance Control Schemes, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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simscape  (MathWorks Inc)
96
MathWorks Inc simscape
Electrical configuration of whole-cell and microchamber voltage clamp. A, Whole-cell clamp speed is limited by τ ≈ Rs * Cm. Stray capacitance (amplifier, pipette holder, and pipette) is typically modeled in a position that does not interfere with voltage-clamp speed, but can influence measured high-frequency currents if not compensated. B, The microchamber partitions the cell partway within the orifice of the macropipette. Stray Cs1 is as with whole-cell mode. The frequency response of voltage clamp also depends on Rs and Cm, since stray Cs2, if it contributes at all, is dominated by Cm. The configuration in the figure is for a cell midway in the microchamber, membrane Cm equally divided. At high frequencies, the input capacitance will be the series combination of Cm/2 and Cm/2, giving a value of Cm/4. Thus, τ ≈ Rs * Cm/4 provides a faster clamp than whole cell, but the configuration suffers from lack of DC voltage-clamp control across the membranes. With partitioning of the cell more or less within the chamber, the series combination of the nonequal partitioned cell Cm will provide an input Cm less than the smaller of the two partitioned capacitances, regardless of its location inside or outside the microchamber. Thus, clamp τ for both inserted and extruded membranes will have the same U-shaped speed function, being slowest at the half-inserted condition, as depicted. C, Displayed are two current traces (ta and tb) generated by a Matlab <t>Simscape</t> microchamber model using a voltage protocol similar to our DC off-set AC voltage protocol (Fig. 10B, inset). The red trace (also marked with a downward red triangle) is at zero offset, and the blue trace (also marked with an upward blue triangle) is at an offset of −65 mV. Black lines are single exponential fits. Under voltage clamp, the time course of capacitive currents mirrors the time course of the voltage delivered to the cell membrane, as shown in D and E. See text for more details.
Simscape, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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control system matlab simulink model  (MathWorks Inc)
96
MathWorks Inc control system matlab simulink model
Electrical configuration of whole-cell and microchamber voltage clamp. A, Whole-cell clamp speed is limited by τ ≈ Rs * Cm. Stray capacitance (amplifier, pipette holder, and pipette) is typically modeled in a position that does not interfere with voltage-clamp speed, but can influence measured high-frequency currents if not compensated. B, The microchamber partitions the cell partway within the orifice of the macropipette. Stray Cs1 is as with whole-cell mode. The frequency response of voltage clamp also depends on Rs and Cm, since stray Cs2, if it contributes at all, is dominated by Cm. The configuration in the figure is for a cell midway in the microchamber, membrane Cm equally divided. At high frequencies, the input capacitance will be the series combination of Cm/2 and Cm/2, giving a value of Cm/4. Thus, τ ≈ Rs * Cm/4 provides a faster clamp than whole cell, but the configuration suffers from lack of DC voltage-clamp control across the membranes. With partitioning of the cell more or less within the chamber, the series combination of the nonequal partitioned cell Cm will provide an input Cm less than the smaller of the two partitioned capacitances, regardless of its location inside or outside the microchamber. Thus, clamp τ for both inserted and extruded membranes will have the same U-shaped speed function, being slowest at the half-inserted condition, as depicted. C, Displayed are two current traces (ta and tb) generated by a Matlab <t>Simscape</t> microchamber model using a voltage protocol similar to our DC off-set AC voltage protocol (Fig. 10B, inset). The red trace (also marked with a downward red triangle) is at zero offset, and the blue trace (also marked with an upward blue triangle) is at an offset of −65 mV. Black lines are single exponential fits. Under voltage clamp, the time course of capacitive currents mirrors the time course of the voltage delivered to the cell membrane, as shown in D and E. See text for more details.
Control System Matlab Simulink Model, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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system generator block sets  (Xilinx Inc)
90
Xilinx Inc system generator block sets
Electrical configuration of whole-cell and microchamber voltage clamp. A, Whole-cell clamp speed is limited by τ ≈ Rs * Cm. Stray capacitance (amplifier, pipette holder, and pipette) is typically modeled in a position that does not interfere with voltage-clamp speed, but can influence measured high-frequency currents if not compensated. B, The microchamber partitions the cell partway within the orifice of the macropipette. Stray Cs1 is as with whole-cell mode. The frequency response of voltage clamp also depends on Rs and Cm, since stray Cs2, if it contributes at all, is dominated by Cm. The configuration in the figure is for a cell midway in the microchamber, membrane Cm equally divided. At high frequencies, the input capacitance will be the series combination of Cm/2 and Cm/2, giving a value of Cm/4. Thus, τ ≈ Rs * Cm/4 provides a faster clamp than whole cell, but the configuration suffers from lack of DC voltage-clamp control across the membranes. With partitioning of the cell more or less within the chamber, the series combination of the nonequal partitioned cell Cm will provide an input Cm less than the smaller of the two partitioned capacitances, regardless of its location inside or outside the microchamber. Thus, clamp τ for both inserted and extruded membranes will have the same U-shaped speed function, being slowest at the half-inserted condition, as depicted. C, Displayed are two current traces (ta and tb) generated by a Matlab <t>Simscape</t> microchamber model using a voltage protocol similar to our DC off-set AC voltage protocol (Fig. 10B, inset). The red trace (also marked with a downward red triangle) is at zero offset, and the blue trace (also marked with an upward blue triangle) is at an offset of −65 mV. Black lines are single exponential fits. Under voltage clamp, the time course of capacitive currents mirrors the time course of the voltage delivered to the cell membrane, as shown in D and E. See text for more details.
System Generator Block Sets, supplied by Xilinx Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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circuit model  (MathWorks Inc)
94
MathWorks Inc circuit model
Electrical configuration of whole-cell and microchamber voltage clamp. A, Whole-cell clamp speed is limited by τ ≈ Rs * Cm. Stray capacitance (amplifier, pipette holder, and pipette) is typically modeled in a position that does not interfere with voltage-clamp speed, but can influence measured high-frequency currents if not compensated. B, The microchamber partitions the cell partway within the orifice of the macropipette. Stray Cs1 is as with whole-cell mode. The frequency response of voltage clamp also depends on Rs and Cm, since stray Cs2, if it contributes at all, is dominated by Cm. The configuration in the figure is for a cell midway in the microchamber, membrane Cm equally divided. At high frequencies, the input capacitance will be the series combination of Cm/2 and Cm/2, giving a value of Cm/4. Thus, τ ≈ Rs * Cm/4 provides a faster clamp than whole cell, but the configuration suffers from lack of DC voltage-clamp control across the membranes. With partitioning of the cell more or less within the chamber, the series combination of the nonequal partitioned cell Cm will provide an input Cm less than the smaller of the two partitioned capacitances, regardless of its location inside or outside the microchamber. Thus, clamp τ for both inserted and extruded membranes will have the same U-shaped speed function, being slowest at the half-inserted condition, as depicted. C, Displayed are two current traces (ta and tb) generated by a Matlab <t>Simscape</t> microchamber model using a voltage protocol similar to our DC off-set AC voltage protocol (Fig. 10B, inset). The red trace (also marked with a downward red triangle) is at zero offset, and the blue trace (also marked with an upward blue triangle) is at an offset of −65 mV. Black lines are single exponential fits. Under voltage clamp, the time course of capacitive currents mirrors the time course of the voltage delivered to the cell membrane, as shown in D and E. See text for more details.
Circuit Model, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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matlab control system toolbox  (MathWorks Inc)
96
MathWorks Inc matlab control system toolbox
Electrical configuration of whole-cell and microchamber voltage clamp. A, Whole-cell clamp speed is limited by τ ≈ Rs * Cm. Stray capacitance (amplifier, pipette holder, and pipette) is typically modeled in a position that does not interfere with voltage-clamp speed, but can influence measured high-frequency currents if not compensated. B, The microchamber partitions the cell partway within the orifice of the macropipette. Stray Cs1 is as with whole-cell mode. The frequency response of voltage clamp also depends on Rs and Cm, since stray Cs2, if it contributes at all, is dominated by Cm. The configuration in the figure is for a cell midway in the microchamber, membrane Cm equally divided. At high frequencies, the input capacitance will be the series combination of Cm/2 and Cm/2, giving a value of Cm/4. Thus, τ ≈ Rs * Cm/4 provides a faster clamp than whole cell, but the configuration suffers from lack of DC voltage-clamp control across the membranes. With partitioning of the cell more or less within the chamber, the series combination of the nonequal partitioned cell Cm will provide an input Cm less than the smaller of the two partitioned capacitances, regardless of its location inside or outside the microchamber. Thus, clamp τ for both inserted and extruded membranes will have the same U-shaped speed function, being slowest at the half-inserted condition, as depicted. C, Displayed are two current traces (ta and tb) generated by a Matlab <t>Simscape</t> microchamber model using a voltage protocol similar to our DC off-set AC voltage protocol (Fig. 10B, inset). The red trace (also marked with a downward red triangle) is at zero offset, and the blue trace (also marked with an upward blue triangle) is at an offset of −65 mV. Black lines are single exponential fits. Under voltage clamp, the time course of capacitive currents mirrors the time course of the voltage delivered to the cell membrane, as shown in D and E. See text for more details.
Matlab Control System Toolbox, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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finite control set model predictive controller  (MathWorks Inc)
95
MathWorks Inc finite control set model predictive controller
Electrical configuration of whole-cell and microchamber voltage clamp. A, Whole-cell clamp speed is limited by τ ≈ Rs * Cm. Stray capacitance (amplifier, pipette holder, and pipette) is typically modeled in a position that does not interfere with voltage-clamp speed, but can influence measured high-frequency currents if not compensated. B, The microchamber partitions the cell partway within the orifice of the macropipette. Stray Cs1 is as with whole-cell mode. The frequency response of voltage clamp also depends on Rs and Cm, since stray Cs2, if it contributes at all, is dominated by Cm. The configuration in the figure is for a cell midway in the microchamber, membrane Cm equally divided. At high frequencies, the input capacitance will be the series combination of Cm/2 and Cm/2, giving a value of Cm/4. Thus, τ ≈ Rs * Cm/4 provides a faster clamp than whole cell, but the configuration suffers from lack of DC voltage-clamp control across the membranes. With partitioning of the cell more or less within the chamber, the series combination of the nonequal partitioned cell Cm will provide an input Cm less than the smaller of the two partitioned capacitances, regardless of its location inside or outside the microchamber. Thus, clamp τ for both inserted and extruded membranes will have the same U-shaped speed function, being slowest at the half-inserted condition, as depicted. C, Displayed are two current traces (ta and tb) generated by a Matlab <t>Simscape</t> microchamber model using a voltage protocol similar to our DC off-set AC voltage protocol (Fig. 10B, inset). The red trace (also marked with a downward red triangle) is at zero offset, and the blue trace (also marked with an upward blue triangle) is at an offset of −65 mV. Black lines are single exponential fits. Under voltage clamp, the time course of capacitive currents mirrors the time course of the voltage delivered to the cell membrane, as shown in D and E. See text for more details.
Finite Control Set Model Predictive Controller, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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voltage relay matlab simulink models  (MathWorks Inc)
92
MathWorks Inc voltage relay matlab simulink models
Electrical configuration of whole-cell and microchamber voltage clamp. A, Whole-cell clamp speed is limited by τ ≈ Rs * Cm. Stray capacitance (amplifier, pipette holder, and pipette) is typically modeled in a position that does not interfere with voltage-clamp speed, but can influence measured high-frequency currents if not compensated. B, The microchamber partitions the cell partway within the orifice of the macropipette. Stray Cs1 is as with whole-cell mode. The frequency response of voltage clamp also depends on Rs and Cm, since stray Cs2, if it contributes at all, is dominated by Cm. The configuration in the figure is for a cell midway in the microchamber, membrane Cm equally divided. At high frequencies, the input capacitance will be the series combination of Cm/2 and Cm/2, giving a value of Cm/4. Thus, τ ≈ Rs * Cm/4 provides a faster clamp than whole cell, but the configuration suffers from lack of DC voltage-clamp control across the membranes. With partitioning of the cell more or less within the chamber, the series combination of the nonequal partitioned cell Cm will provide an input Cm less than the smaller of the two partitioned capacitances, regardless of its location inside or outside the microchamber. Thus, clamp τ for both inserted and extruded membranes will have the same U-shaped speed function, being slowest at the half-inserted condition, as depicted. C, Displayed are two current traces (ta and tb) generated by a Matlab <t>Simscape</t> microchamber model using a voltage protocol similar to our DC off-set AC voltage protocol (Fig. 10B, inset). The red trace (also marked with a downward red triangle) is at zero offset, and the blue trace (also marked with an upward blue triangle) is at an offset of −65 mV. Black lines are single exponential fits. Under voltage clamp, the time course of capacitive currents mirrors the time course of the voltage delivered to the cell membrane, as shown in D and E. See text for more details.
Voltage Relay Matlab Simulink Models, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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simulink environment  (MathWorks Inc)
94
MathWorks Inc simulink environment
Electrical configuration of whole-cell and microchamber voltage clamp. A, Whole-cell clamp speed is limited by τ ≈ Rs * Cm. Stray capacitance (amplifier, pipette holder, and pipette) is typically modeled in a position that does not interfere with voltage-clamp speed, but can influence measured high-frequency currents if not compensated. B, The microchamber partitions the cell partway within the orifice of the macropipette. Stray Cs1 is as with whole-cell mode. The frequency response of voltage clamp also depends on Rs and Cm, since stray Cs2, if it contributes at all, is dominated by Cm. The configuration in the figure is for a cell midway in the microchamber, membrane Cm equally divided. At high frequencies, the input capacitance will be the series combination of Cm/2 and Cm/2, giving a value of Cm/4. Thus, τ ≈ Rs * Cm/4 provides a faster clamp than whole cell, but the configuration suffers from lack of DC voltage-clamp control across the membranes. With partitioning of the cell more or less within the chamber, the series combination of the nonequal partitioned cell Cm will provide an input Cm less than the smaller of the two partitioned capacitances, regardless of its location inside or outside the microchamber. Thus, clamp τ for both inserted and extruded membranes will have the same U-shaped speed function, being slowest at the half-inserted condition, as depicted. C, Displayed are two current traces (ta and tb) generated by a Matlab <t>Simscape</t> microchamber model using a voltage protocol similar to our DC off-set AC voltage protocol (Fig. 10B, inset). The red trace (also marked with a downward red triangle) is at zero offset, and the blue trace (also marked with an upward blue triangle) is at an offset of −65 mV. Black lines are single exponential fits. Under voltage clamp, the time course of capacitive currents mirrors the time course of the voltage delivered to the cell membrane, as shown in D and E. See text for more details.
Simulink Environment, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Electrical configuration of whole-cell and microchamber voltage clamp. A, Whole-cell clamp speed is limited by τ ≈ Rs * Cm. Stray capacitance (amplifier, pipette holder, and pipette) is typically modeled in a position that does not interfere with voltage-clamp speed, but can influence measured high-frequency currents if not compensated. B, The microchamber partitions the cell partway within the orifice of the macropipette. Stray Cs1 is as with whole-cell mode. The frequency response of voltage clamp also depends on Rs and Cm, since stray Cs2, if it contributes at all, is dominated by Cm. The configuration in the figure is for a cell midway in the microchamber, membrane Cm equally divided. At high frequencies, the input capacitance will be the series combination of Cm/2 and Cm/2, giving a value of Cm/4. Thus, τ ≈ Rs * Cm/4 provides a faster clamp than whole cell, but the configuration suffers from lack of DC voltage-clamp control across the membranes. With partitioning of the cell more or less within the chamber, the series combination of the nonequal partitioned cell Cm will provide an input Cm less than the smaller of the two partitioned capacitances, regardless of its location inside or outside the microchamber. Thus, clamp τ for both inserted and extruded membranes will have the same U-shaped speed function, being slowest at the half-inserted condition, as depicted. C, Displayed are two current traces (ta and tb) generated by a Matlab Simscape microchamber model using a voltage protocol similar to our DC off-set AC voltage protocol (Fig. 10B, inset). The red trace (also marked with a downward red triangle) is at zero offset, and the blue trace (also marked with an upward blue triangle) is at an offset of −65 mV. Black lines are single exponential fits. Under voltage clamp, the time course of capacitive currents mirrors the time course of the voltage delivered to the cell membrane, as shown in D and E. See text for more details.

Journal: The Journal of Neuroscience

Article Title: The Frequency Response of Outer Hair Cell Voltage-Dependent Motility Is Limited by Kinetics of Prestin

doi: 10.1523/JNEUROSCI.0425-18.2018

Figure Lengend Snippet: Electrical configuration of whole-cell and microchamber voltage clamp. A, Whole-cell clamp speed is limited by τ ≈ Rs * Cm. Stray capacitance (amplifier, pipette holder, and pipette) is typically modeled in a position that does not interfere with voltage-clamp speed, but can influence measured high-frequency currents if not compensated. B, The microchamber partitions the cell partway within the orifice of the macropipette. Stray Cs1 is as with whole-cell mode. The frequency response of voltage clamp also depends on Rs and Cm, since stray Cs2, if it contributes at all, is dominated by Cm. The configuration in the figure is for a cell midway in the microchamber, membrane Cm equally divided. At high frequencies, the input capacitance will be the series combination of Cm/2 and Cm/2, giving a value of Cm/4. Thus, τ ≈ Rs * Cm/4 provides a faster clamp than whole cell, but the configuration suffers from lack of DC voltage-clamp control across the membranes. With partitioning of the cell more or less within the chamber, the series combination of the nonequal partitioned cell Cm will provide an input Cm less than the smaller of the two partitioned capacitances, regardless of its location inside or outside the microchamber. Thus, clamp τ for both inserted and extruded membranes will have the same U-shaped speed function, being slowest at the half-inserted condition, as depicted. C, Displayed are two current traces (ta and tb) generated by a Matlab Simscape microchamber model using a voltage protocol similar to our DC off-set AC voltage protocol (Fig. 10B, inset). The red trace (also marked with a downward red triangle) is at zero offset, and the blue trace (also marked with an upward blue triangle) is at an offset of −65 mV. Black lines are single exponential fits. Under voltage clamp, the time course of capacitive currents mirrors the time course of the voltage delivered to the cell membrane, as shown in D and E. See text for more details.

Article Snippet: Models were implemented in Matlab Simulink and Simscape, as detailed previously ( Song and Santos-Sacchi, 2013 ; Santos-Sacchi and Song, 2014 ).

Techniques: Transferring, Generated